Oxygen-Induced Retinopathy from Recurrent Intermittent Hypoxia Is Not Dependent on Resolution with Room Air or Oxygen, in Neonatal Rats

Oxygen-Induced Retinopathy from Recurrent Intermittent Hypoxia Is Not Dependent on Resolution with Room Air or Oxygen, in Neonatal Rats

Preterm infants often experience intermittent hypoxia (IH) with resolution in room air (RA) or hyperoxia (Hx) between events. Hypoxia is a major inducer of vascular endothelial growth factor, which plays a key role in normal and aberrant retinal angiogenesis. This study tested the hypothesis that ne...

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Bibliographic Details
Main Authors: Kay D. Beharry, Charles L. Cai, Jacqueline Skelton, Faisal Siddiqui, Christina D’Agrosa, Johanna Calo, Gloria B. Valencia, Jacob V. Aranda
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
angiogenesis
astrocytes
insulin-like growth factor-I
intermittent hypoxia
oxygen-induced retinopathy
retina
vascular endothelial growth factor
Online Access:http://www.mdpi.com/1422-0067/19/5/1337

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http://www.mdpi.com/1422-0067/19/5/1337

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