The restriction of zoonotic PERV transmission by human APOBEC3G.

The human APOBEC3G protein is an innate anti-viral factor that can dominantly inhibit the replication of some endogenous and exogenous retroviruses. The prospects of purposefully harnessing such an anti-viral defense are under investigation. Here, long-term co-culture experiments were used to show t...

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Bibliographic Details
Main Authors: Stefán R Jónsson, Rebecca S LaRue, Mark D Stenglein, Scott C Fahrenkrug, Valgerdur Andrésdóttir, Reuben S Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1963317?pdf=render