Beta2 adrenergic receptor (ADRβ2) haplotype pair (2/4) is associated with severe asthma.

BACKGROUND: β2 adrenergic receptor (ADRβ2) polymorphisms including ADRβ2+46G>A have been reported to cause adverse outcomes in mild asthmatics. The extent to which ADRβ2 polymorphisms and in particular their haplotypes contribute to severe asthma is unknown. OBJECTIVE: To determine the associatio...

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Bibliographic Details
Main Authors: Li Ping Chung, Svetlana Baltic, Manuel Ferreira, Suzanna Temple, Grant Waterer, Philip J Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3972120?pdf=render