Dose-Dependent Neurochemical and Functional Protection Afforded by Encapsulated CNTF-Producing Cells

Intracerebral delivery of hCNTF has shown considerable neuroprotective potential in animal models of Huntington's disease (HD). The present study describes the relationship between a range of hCNTF doses and the resulting behavioral and neurochemical (striatal ChAT and GAD activity) protection...

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Bibliographic Details
Main Author: Dwaine F. Emerich Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2004-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000004783983404