SH Oxidation Stimulates Calcium Release Channels (Ryanodine Receptors) From Excitable Cells

SH Oxidation Stimulates Calcium Release Channels (Ryanodine Receptors) From Excitable Cells

The effects of redox reagents on the activity of the intracellular calcium release channels (ryanodine receptors) of skeletal and cardiac muscle, or brain cortex neurons, was examined. In lipid bilayer experiments, oxidizing agents (2,2'-dithiodipyridine or thimerosal) modified the calcium depe...

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Bibliographic Details
Main Authors: CECILIA HIDALGO, RICARDO BULL, JUAN J MARENGO, CLAUDIO F PÉREZ, PAULINA DONOSO
Format: Article
Language:English
Published: BMC 2000-01-01
Series:Biological Research
Subjects:
calcium dependence
neurons
redox state
ryanodine receptors
sarcoplasmic reticulum
skeletal and cardiac muscle
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200011

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200011

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