Syncytin 1, CD9, and CD47 regulating cell fusion to form PGCCs associated with cAMP/PKA and JNK signaling pathway

Syncytin 1, CD9, and CD47 regulating cell fusion to form PGCCs associated with cAMP/PKA and JNK signaling pathway

Abstract Background We have previously reported the formation of polyploid giant cancer cells (PGCCs) through endoreduplication or cell fusion after cobalt chloride (CoCl2) induction. Cell fusion plays an important role in development and disease. However, the underlying molecular mechanism concerni...

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Bibliographic Details
Main Authors: Fei Fei, Chunyuan Li, Xinlu Wang, Jiaxing Du, Kai Liu, Bo Li, Peiyu Yao, Yuwei Li, Shiwu Zhang
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Cancer Medicine
Subjects:
cell fusion
colorectal cancer
polyploid giant cancer cells
syncytin 1
Online Access:https://doi.org/10.1002/cam4.2173

Internet

https://doi.org/10.1002/cam4.2173

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