Apolipoprotein E plays a key role against cryptosporidial infection in transgenic undernourished mice.

Apolipoliprotein E (apoE), a critical targeting protein in lipid homeostasis, has been found to have immunoinflammatory effects on murine models of infection and malnutrition. The effects of apoE in undernourished and Cryptosporidium parvum-infected mice have not been investigated. In order to study...

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Bibliographic Details
Main Authors: Orleâncio G R Azevedo, David T Bolick, James K Roche, Relana F Pinkerton, Aldo A M Lima, Michael P Vitek, Cirle A Warren, Reinaldo B Oriá, Richard L Guerrant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938486?pdf=render