-Synuclein as CSF and Blood Biomarker of Dementia with Lewy Bodies

Dementia with Lewy bodies (DLB) is a common subtype of dementia in the elderly. DLB is neuropathologically characterized by the presence of Lewy bodies and Lewy neurites, both of which are composed of α-synuclein. Although α-synuclein was initially considered to be an exclusively intracellular prote...

Full description

Bibliographic Details
Main Authors: Kensaku Kasuga, Masatoyo Nishizawa, Takeshi Ikeuchi
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.1155/2012/437025