A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia

A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia

Abstract Background Hyperprolactinemia (HPRL) is a classical side effect of antipsychotic drugs primarily attributed to blockade of dopamine D2 receptors (DRD2s) on the membranes of lactotroph cells within the pituitary gland. Certain antipsychotic drugs, e.g. risperidone, are more likely to induce...

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Bibliographic Details
Main Authors: Diana Z. Osmanova, Maxim B. Freidin, Olga Yu. Fedorenko, Ivan V. Pozhidaev, Anastasiia S. Boiko, Natalia M. Vyalova, Vladimir V. Tiguntsev, Elena G. Kornetova, Anton J. M. Loonen, Arkadiy V. Semke, Bob Wilffert, Nikolay A. Bokhan, Svetlana A. Ivanova
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Medical Genetics
Subjects:
Dopamine receptors genes
Dopamine transporter SLC6A3
Monoamine oxidase (MAO)
Antipsychotics
Hyperprolactinemia
Online Access:http://link.springer.com/article/10.1186/s12881-019-0773-3

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http://link.springer.com/article/10.1186/s12881-019-0773-3

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