A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury.

A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury.

The principles of Refinement, Replacement and Reduction (3R's) should be taken into account when animals must be used for scientific purpose. Here, a Reduction / Refinement approach was applied to the procedure of spinal cord injury (SCI), an animal model used in rehabilitation medicine researc...

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Bibliographic Details
Main Authors: Veronica Redaelli, Simonetta Papa, Gerardo Marsella, Giuliano Grignaschi, Alice Bosi, Nicola Ludwig, Fabio Luzi, Irma Vismara, Stefano Rimondo, Pietro Veglianese, Svetlana Tepteva, Silvia Mazzola, Pietro Zerbi, Luca Porcu, John V Roughan, Gianfranco Parati, Laura Calvillo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224337

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https://doi.org/10.1371/journal.pone.0224337

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