Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.

Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.

Nucleotide Excision Repair (NER), which removes a variety of helix-distorting lesions from DNA, is initiated by two distinct DNA damage-sensing mechanisms. Transcription Coupled Repair (TCR) removes damage from the active strand of transcribed genes and depends on the SWI/SNF family protein CSB. Glo...

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Bibliographic Details
Main Authors: Hannes Lans, Jurgen A Marteijn, Björn Schumacher, Jan H J Hoeijmakers, Gert Jansen, Wim Vermeulen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2865526?pdf=render

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http://europepmc.org/articles/PMC2865526?pdf=render

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