Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFNγ Production From Human Colonic ILC3s via Multiple Mechanisms

Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFNγ Production From Human Colonic ILC3s via Multiple Mechanisms

Innate lymphoid cells (ILCs) are a diverse family of cells that play critical roles in mucosal immunity. One subset of the ILC family, Group 3 ILCs (ILC3s), has been shown to aid in gut homeostasis through the production of IL-22. IL-22 promotes gut homeostasis through its functional effect on the e...

Full description

Bibliographic Details
Main Authors: Moriah J. Castleman, Stephanie M. Dillon, Christine M. Purba, Andrew C. Cogswell, Jon J. Kibbie, Martin D. McCarter, Mario L. Santiago, Edward Barker, Cara C. Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
human
innate lymphoid cells
commensal bacteria
colonic mucosa
NKp44
myeloid dendritic cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00649/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00649/full

Similar Items