Myeloid derived suppressor cells are present at high frequency in neonates and suppress in vitro T cell responses.

Over 4 million infants die each year from infections, many of which are vaccine-preventable. Young infants respond relatively poorly to many infections and vaccines, but the basis of reduced immunity in infants is ill defined. We sought to investigate whether myeloid-derived suppressor cells (MDSC)...

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Bibliographic Details
Main Authors: Ana Gervassi, Nicholas Lejarcegui, Sandra Dross, Amanda Jacobson, Grace Itaya, Elvis Kidzeru, Soren Gantt, Heather Jaspan, Helen Horton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4172591?pdf=render