Combination of Proteogenomics with Peptide De Novo Sequencing Identifies New Genes and Hidden Posttranscriptional Modifications

Combination of Proteogenomics with Peptide De Novo Sequencing Identifies New Genes and Hidden Posttranscriptional Modifications

Next-generation sequencing techniques have considerably increased the number of completely sequenced eukaryotic genomes. These genomes are mostly automatically annotated, and ab initio gene prediction is commonly combined with homology-based search approaches and often supported by transcriptomic da...

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Bibliographic Details
Main Authors: B. Blank-Landeshammer, I. Teichert, R. Märker, M. Nowrousian, U. Kück, A. Sickmann
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mBio
Subjects:
proteogenomics
peptide de novo sequencing
rna editing
alternative splicing
phylostratigraphy
gene ontology
alternative splice sites
fungal genome
genomics
proteomics
Online Access:https://doi.org/10.1128/mBio.02367-19

Internet

https://doi.org/10.1128/mBio.02367-19

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