Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXRα) and Pregnane X Receptor (PXR)

Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXRα) and Pregnane X Receptor (PXR)

Liver X receptor (LXR) is a nuclear receptor that regulates various biological processes, including de novo lipogenesis, cholesterol metabolism, and inflammation. Selective inhibition of LXR may aid the treatment of nonalcoholic fatty liver disease (NAFLD). Sesamin is a naturally occurring lignan in...

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Bibliographic Details
Main Authors: Tsai-Sung Tai, Ni Tien, Hsin-Yi Shen, Fang-Yi Chu, Charles C. N. Wang, Chieh-Hsiang Lu, Hui-I Yu, Fang-Ping Kung, Hsiang-Hsun Chuang, Ying-Ray Lee, Hsiao-Yun Chang, Yun-Ping Lim
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2019/9401648

Internet

http://dx.doi.org/10.1155/2019/9401648

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