Mouse models of polycystic kidney disease induced by defects of ciliary proteins

Polycystic kidney disease (PKD) is a common hereditarydisorder which is characterized by fluid-filled cysts in thekidney. Mutation in either PKD1, encoding polycystin-1 (PC1),or PKD2, encoding polycystin-2 (PC2), are causative genes ofPKD. Recent studies indicate that renal cilia, known asmechanosen...

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Bibliographic Details
Main Authors: Je Yeong Ko, Jong Hoon Park
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-02-01
Series:BMB Reports
Subjects:
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI2MTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0yJTVEMTMwMjI2MTQzN18lMjgwNzMtMDc5JTI5Qk1CXzEzLTAyMi5wZGY=