Immuno-Modulatory and Anti-Inflammatory Effects of Dihydrogracilin A, a Terpene Derived from the Marine Sponge Dendrilla membranosa

Immuno-Modulatory and Anti-Inflammatory Effects of Dihydrogracilin A, a Terpene Derived from the Marine Sponge Dendrilla membranosa

We assessed the immunomodulatory and anti-inflammatory effects of 9,11-dihydrogracilin A (DHG), a molecule derived from the Antarctic marine sponge Dendrilla membranosa. We used in vitro and in vivo approaches to establish DHG properties. Human peripheral blood mononuclear cells (PBMC) and human ker...

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Bibliographic Details
Main Authors: Elena Ciaglia, Anna Maria Malfitano, Chiara Laezza, Angelo Fontana, Genoveffa Nuzzo, Adele Cutignano, Mario Abate, Marco Pelin, Silvio Sosa, Maurizio Bifulco, Patrizia Gazzerro
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:International Journal of Molecular Sciences
Subjects:
marine sponge
natural compound
inflammation
lymphocytes
Online Access:https://www.mdpi.com/1422-0067/18/8/1643

Internet

https://www.mdpi.com/1422-0067/18/8/1643

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