Application of a MRI Based Severity Index to Longitudinal Atrophy Change in Alzheimer’s Disease, Mild Cognitive Impairment and Healthy Older Individuals in the AddNeuroMed cohort

Application of a MRI Based Severity Index to Longitudinal Atrophy Change in Alzheimer’s Disease, Mild Cognitive Impairment and Healthy Older Individuals in the AddNeuroMed cohort

Cross sectional studies of patients at risk of developing Alzheimer disease (AD) have identified several brain regions known to be prone to degeneration suitable as biomarkers, including hippocampal, ventricular and whole brain volume. The aim of this study was to longitudinally evaluate an index ba...

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Bibliographic Details
Main Authors: Carlos eAguilar, J-Sebastian eMuehlboeck, Patrizia eMecocci, Bruno eVellas, Magda eTsolaki, Iwona eKloszewska, Hilkka eSoininen, Simon eLovestone, Lars-Olof eWahlund, Andrew eSimmons, Eric eWestman
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
MRI
multivariate statistics
Alzheimer’s disease
MCI
ApoE4
OPLS
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00145/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00145/full

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