2,6-DMBQ suppresses cell proliferation and migration via inhibiting mTOR/AKT and p38 MAPK signaling pathways in NSCLC cells

2,6-DMBQ suppresses cell proliferation and migration via inhibiting mTOR/AKT and p38 MAPK signaling pathways in NSCLC cells

2,6-Dimethoxy-1,4-benzoquinone (2,6-DMBQ) is the major bioactive compound found in fermented wheat germ extract. Although fermented wheat germ extract has been reported to show anti-proliferative and anti-metabolic effects in various cancers, the anticancer potential and molecular mechanisms exerted...

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Bibliographic Details
Main Authors: Xiaomeng Xie, Xueyin Zu, Kyle Laster, Zigang Dong, Dong Joon Kim
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Pharmacological Sciences
Subjects:
2,6-DMBQ
Proliferation
AKT
p38 MAPK
NSCLC cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000049

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http://www.sciencedirect.com/science/article/pii/S1347861321000049

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