Adaptive robust control of cancer chemotherapy with extended Kalman filter observer
In this paper we control the amount of three major biological cell types (normal, immune and tumor cells) under uncertainty in cancer model parameters, using different chemotherapy drug dosages. To achieve this goal, an adaptive robust controller is proposed for a third order nonlinear model, which...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-01-01
|
| Series: | Informatics in Medicine Unlocked |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914817300060 |