Frequency of aberrant promoter methylation of p15INK4b and O6-methylguanine-DNA methyltransferase genes in b-cell non-Hodgkin lymphoma: A pilot study

The methylation status of the target promoter sequences of p15INK4B (p15) and O6-methylguanine-DNA methyltransferase (MGMT) genes was studied by methylation-specific PCR in 10 adult patients with de novo B-cell non- Hodgkin lymphoma (B-NHL). The aberrant hypermethylation of the p15 gene was more fre...

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Bibliographic Details
Main Authors: Kraguljac-Kurtović Nada, Krajnović Milena, Dimitrijević B., Mihaljević Biljana, Gotić Mirjana, Krtolica Koviljka
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2010-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641002211K.pdf