Frequency of aberrant promoter methylation of p15INK4b and O6-methylguanine-DNA methyltransferase genes in b-cell non-Hodgkin lymphoma: A pilot study
The methylation status of the target promoter sequences of p15INK4B (p15) and O6-methylguanine-DNA methyltransferase (MGMT) genes was studied by methylation-specific PCR in 10 adult patients with de novo B-cell non- Hodgkin lymphoma (B-NHL). The aberrant hypermethylation of the p15 gene was more fre...
Main Authors: | Kraguljac-Kurtović Nada, Krajnović Milena, Dimitrijević B., Mihaljević Biljana, Gotić Mirjana, Krtolica Koviljka |
---|---|
Format: | Article |
Language: | English |
Published: |
University of Belgrade, University of Novi Sad
2010-01-01
|
Series: | Archives of Biological Sciences |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641002211K.pdf |
Similar Items
-
O6-methylguanine-DNA Methyltransferase Promoter Methylation in Patients with Rectal Adenocarcinoma After Chemoradiotherapy Treatment: Clinical Implications
by: Jaime A. Oliver, et al.
Published: (2019-09-01) -
O-6-methylguanine-DNA methyltransferase promoter methylation can change in glioblastoma recurrence due to intratumor heterogeneity
by: Valeria Barresi, et al.
Published: (2018-01-01) -
The Clinical Significance of O6-Methylguanine-DNA Methyltransferase Promoter Methylation Status in Adult Patients With Glioblastoma: A Meta-analysis
by: Yu-Hang Zhao, et al.
Published: (2018-03-01) -
Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treatment with Temozolomide In Vitro and In Vivo
by: Thomas C. Chen, et al.
Published: (2018-09-01) -
Evaluation of prognostic utility of Ki-67, P53, and O-6-methylguanine-DNA methyltransferase expression in pituitary tumors
by: Chhanda Das, et al.
Published: (2019-10-01)