Imputation and Reanalysis of ExomeChip Data Identifies Novel, Conditional and Joint Genetic Effects on Parkinson’s Disease Risk

Given that improved imputation software and high-coverage whole genome sequence (WGS)-based haplotype reference panels now enable inexpensive approximation of WGS genotype data, we hypothesised that WGS-based imputation and analysis of existing ExomeChip-based genome-wide association (GWA) data will...

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Bibliographic Details
Main Authors: Linduni M. Rodrigo, Dale R. Nyholt
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/5/689