MicroRNAs of bone marrow mesenchymal stem cell-derived exosomes regulate acute myeloid leukemia cell proliferation and apoptosis

Abstract. Background:. Acute myeloid leukemia (AML) is a malignant hematological disease, originating from hematopoiesis stem cell differentiation obstruction and clonal proliferation. New reagents or biologicals for the treatment of AML are urgently needed, and exosomes have been identified as cand...

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Bibliographic Details
Main Authors: Yi-Chuan Xu, Yan-Si Lin, Ling Zhang, Ying Lu, Yan-Ling Sun, Zhi-Gang Fang, Zi-Yu Li, Rui-Fang Fan, Peng Lyu.
Format: Article
Language:English
Published: Wolters Kluwer 2020-12-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001138