Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model

Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model

Mutations in the GJB2 gene [which encodes connexin 26 (Cx26)] are the most common causes of hereditary hearing loss in humans, and previous studies showed postnatal development arrest of the organ of Corti in different Cx26-null mouse models. To explore the pathological changes and the mechanism beh...

Full description

Bibliographic Details
Main Authors: Sen Chen, Le Xie, Kai Xu, Hai-Yan Cao, Xia Wu, Xiao-Xiang Xu, Yu Sun, Wei-Jia Kong
Format: Article
Language:English
Published: The Company of Biologists 2018-02-01
Series:Disease Models & Mechanisms
Subjects:
Connexin26
Cochlear development
Gjb2
Hearing loss
Online Access:http://dmm.biologists.org/content/11/2/dmm033019

Internet

http://dmm.biologists.org/content/11/2/dmm033019

Similar Items