Rab-3 and unc-18 interactions in alcohol sensitivity are distinct from synaptic transmission.

The molecular mechanisms underlying sensitivity to alcohol are incompletely understood. Recent research has highlighted the involvement of two presynaptic proteins, Munc18 and Rab3. We have previously characterised biochemically a number of specific Munc18 point mutations including an E466K mutation...

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Bibliographic Details
Main Authors: James R Johnson, Sudhanva Kashyap, Kim Rankin, Jeff W Barclay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828271?pdf=render