Rab-3 and unc-18 interactions in alcohol sensitivity are distinct from synaptic transmission.
The molecular mechanisms underlying sensitivity to alcohol are incompletely understood. Recent research has highlighted the involvement of two presynaptic proteins, Munc18 and Rab3. We have previously characterised biochemically a number of specific Munc18 point mutations including an E466K mutation...
Main Authors: | James R Johnson, Sudhanva Kashyap, Kim Rankin, Jeff W Barclay |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3828271?pdf=render |
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