Can circulating tumor DNA be used for direct and early stage cancer detection? [version 1; referees: 2 approved]

In the August 16th issue of Science Translational Medicine, Phallen et al propose a method for early cancer diagnosis by using circulating tumor DNA (1). One major advance of this paper includes optimized sequencing of cell-free/circulating tumor DNA (ctDNA) without knowledge of tumor mutations. Eva...

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Bibliographic Details
Main Authors: Eleftherios P Diamandis, Clare Fiala
Format: Article
Language:English
Published: F1000 Research Ltd 2017-12-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-2129/v1