CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells

CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells

Summary: Cancer-initiating cells (CICs) have been implicated in tumor development and aggressiveness. In ovarian carcinoma (OC), CICs drive tumor formation, dissemination, and recurrence, as well as drug resistance, thus accounting for the high death-to-incidence ratio of this neoplasm. However, the...

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Bibliographic Details
Main Authors: Michela Lupia, Francesca Angiolini, Giovanni Bertalot, Stefano Freddi, Kris F. Sachsenmeier, Elisa Chisci, Barbara Kutryb-Zajac, Stefano Confalonieri, Ryszard T. Smolenski, Roberto Giovannoni, Nicoletta Colombo, Fabrizio Bianchi, Ugo Cavallaro
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118301000

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http://www.sciencedirect.com/science/article/pii/S2213671118301000

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