Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases.

Selective and irreversible inhibitors of mosquito acetylcholinesterases for controlling malaria and other mosquito-borne diseases.

New insecticides are urgently needed because resistance to current insecticides allows resurgence of disease-transmitting mosquitoes while concerns for human toxicity from current compounds are growing. We previously reported the finding of a free cysteine (Cys) residue at the entrance of the active...

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Bibliographic Details
Main Authors: Yuan-Ping Pang, Fredrik Ekström, Gregory A Polsinelli, Yang Gao, Sandeep Rana, Duy H Hua, Björn Andersson, Per Ola Andersson, Lei Peng, Sanjay K Singh, Rajesh K Mishra, Kun Yan Zhu, Ann M Fallon, David W Ragsdale, Stephen Brimijoin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2731169?pdf=render

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http://europepmc.org/articles/PMC2731169?pdf=render

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