Impaired function of bone marrow stromal cells in systemic mastocytosis

Patients with systemic mastocytosis (SM) have a wide variety of problems, including skeletal abnormalities. The disease results from a mutation of the stem cell receptor (c-kit) in mast cells and we wondered if the function of bone marrow stromal cells (BMSCs; also known as MSCs or mesenchymal stem...

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Bibliographic Details
Main Authors: Krisztian Nemeth, Todd M. Wilson, Jiaqiang J. Ren, Marianna Sabatino, David M. Stroncek, Miklos Krepuska, Yun Bai, Pamela G. Robey, Dean D. Metcalfe, Eva Mezey
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115000471