Impaired function of bone marrow stromal cells in systemic mastocytosis
Patients with systemic mastocytosis (SM) have a wide variety of problems, including skeletal abnormalities. The disease results from a mutation of the stem cell receptor (c-kit) in mast cells and we wondered if the function of bone marrow stromal cells (BMSCs; also known as MSCs or mesenchymal stem...
Main Authors: | Krisztian Nemeth, Todd M. Wilson, Jiaqiang J. Ren, Marianna Sabatino, David M. Stroncek, Miklos Krepuska, Yun Bai, Pamela G. Robey, Dean D. Metcalfe, Eva Mezey |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-07-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506115000471 |
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