Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum.

Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum.

Generation of potent anti-HIV antibody responses in mucosal compartments is a potential requirement of a transmission-blocking HIV vaccine. HIV-specific, functional antibody responses are present in breast milk, and these mucosal antibody responses may play a role in protection of the majority of HI...

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Bibliographic Details
Main Authors: James Friedman, S Munir Alam, Xiaoying Shen, Shi-Mao Xia, Shelley Stewart, Kara Anasti, Justin Pollara, Genevieve G Fouda, Guang Yang, Garnett Kelsoe, Guido Ferrari, Georgia D Tomaras, Barton F Haynes, Hua-Xin Liao, M Anthony Moody, Sallie R Permar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3356285?pdf=render

Internet

http://europepmc.org/articles/PMC3356285?pdf=render

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