Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination

Chromatin architecture is a key regulator of transcriptional processes, however current methods to investigate it have technical limitations. Here, the authors describe a novel chromatin capture technique, CATCH, which can be used to identify and characterize complex genomic interaction networks.

Bibliographic Details
Main Authors: Ryan J. Bourgo, Hari Singhal, Geoffrey L. Greene
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12893