Paralogues From the Expanded Tlr11 Gene Family in Mudskipper (Boleophthalmus pectinirostris) Are Under Positive Selection and Respond Differently to LPS/Poly(I:C) Challenge

Paralogues From the Expanded Tlr11 Gene Family in Mudskipper (Boleophthalmus pectinirostris) Are Under Positive Selection and Respond Differently to LPS/Poly(I:C) Challenge

Toll-like receptors (TLRs) are major molecular pattern recognition receptors, which are essential for triggering a series of innate immune responses against invading pathogens by recognizing their evolutionary conserved molecular patterns. The mudskipper, Boleophthalmus pectinirostris is exceptional...

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Bibliographic Details
Main Authors: Heng Tong Qiu, Jorge M. O. Fernandes, Wan Shu Hong, Hai Xu Wu, Yu Ting Zhang, Sheng Huang, Dong Teng Liu, Hui Yu, Qiong Wang, Xin Xin You, Shi Xi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
Boleophthalmus pectinirostris
TLR21
TLR22
TLR23
innate immunity
positive selection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00343/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00343/full

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