The Anticoagulant Effect of PGI2S and tPA in Transgenic Umbilical Vein Endothelial Cells Is Linked to Up-Regulation of PKA and PKC

The Anticoagulant Effect of PGI2S and tPA in Transgenic Umbilical Vein Endothelial Cells Is Linked to Up-Regulation of PKA and PKC

The selection of vascular grafts for coronary artery bypass surgery is crucial for a positive outcome. This study aimed to establish a novel line of vascular endothelial cells with a potent anticoagulant effect. A lentiviral vector was used to stably transfect human umbilical vein endothelial cells...

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Bibliographic Details
Main Authors: Jian-Hua Wang, Lin-Jing Yuan, Zhi-Min Zhong, Zhe-Sheng Wen, Jian-Ming Deng, Rong-Xin Liang, Min Zheng
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:International Journal of Molecular Sciences
Subjects:
anticoagulant
coronary artery bypass graft
endothelial cells
PGI2S
tPA
Online Access:http://www.mdpi.com/1422-0067/15/2/2826

Internet

http://www.mdpi.com/1422-0067/15/2/2826

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