Frustrated phagocytosis on micro-patterned immune complexes to characterize lysosome movements in live macrophages.

Frustrated phagocytosis on micro-patterned immune complexes to characterize lysosome movements in live macrophages.

Lysosome mobilization is a key cellular process in phagocytes for bactericidal activities and trans-matrix migration. The molecular mechanisms that regulate lysosome mobilization are still poorly known. Lysosomes are hard to track as they move towards phagosomes throughout the cell volume. In order...

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Bibliographic Details
Main Authors: Arnaud M. Labrousse, Etienne eMeunier, Julien eRecord, Anna eLabernadie, Amélie eBeduer, Christophe eVieu, Thouraya eBen Safta, Isabelle eMaridonneau-Parini
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Immunology
Subjects:
Macrophages
frustrated phagocytosis
Lysosome
micro-patterned immune complexes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00051/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00051/full

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