Mechanism of insulin resistance in adipocytes of rats fed a high-fat diet.

Insulin's ability to stimulate glucose metabolism is severely diminished in the adipose tissue of rats fed a high-fat diet as compared to that of rats fed a low-fat diet. To elucidate the mechanism for this effect we have measured the binding of insulin, the hormone effect on 2-deoxyglucose upt...

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Bibliographic Details
Main Authors: M Lavau, S K Fried, C Susini, P Freychet
Format: Article
Language:English
Published: Elsevier 1979-01-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520406455