Development of novel lutein nanocrystal formulation with improved oral bioavailability and ocular distribution

A nanocrystal formulation of lutein (NC/LT) was prepared by particle size reduction approach with a bottom-up system to improve nutraceutical properties of LT, and physicochemical and pharmacokinetic characterizations of NC/LT were undertaken. In NC/LT, LT nanoparticles with a mean diameter of 230 n...

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Bibliographic Details
Main Authors: Yoshiki Seto, Kodai Ueno, Hiroki Suzuki, Hideyuki Sato, Satomi Onoue
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619304232