3,3′-Diindolylmethane protects cardiomyocytes from LPS-induced inflammatory response and apoptosis

3,3′-Diindolylmethane protects cardiomyocytes from LPS-induced inflammatory response and apoptosis

Abstract Background 3,3′-Diindolylmethane (DIM) has been extensively studied as a potential therapeutic drug with free radical scavenging, antioxidant and anti-angiogenic effects. However, whether DIM has similar effects on cardiomyocytes remains unknown. Here we evaluated DIM’s influence on inflamm...

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Bibliographic Details
Main Authors: Qiang Luo, Ankang Yang, Quan Cao, Hongjing Guan
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Pharmacology and Toxicology
Subjects:
DIM
LPS
Septic cardiomyopathy
ROS
H9C2
NFκB
Online Access:http://link.springer.com/article/10.1186/s40360-018-0262-x

Internet

http://link.springer.com/article/10.1186/s40360-018-0262-x

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