Rosmarinic acid inhibits proliferation and invasion of hepatocellular carcinoma cells SMMC 7721 via PI3K/AKT/mTOR signal pathway

Objective: To investigate the effect of rosmarinic acid (RosA) on hepatocellular carcinoma cell in vivo and in vitro and to explore its possible mechanism of anti-hepatocarcinoma. Methods: The hepatocellular carcinoma cell line SMMC-7721 was treated with different concentrations of RosA (0, 20, 50,...

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Bibliographic Details
Main Authors: Li Wang, Huiyu Yang, Chen Wang, Xiaoxin Shi, Kunkun Li
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219324722