Transmissible inflammation-induced colorectal cancer in inflammasome-deficient mice

The microbiota is pivotal in orchestrating the pathogenesis of IBD-associated colorectal cancer (CRC). We recently demonstrated that altered elements in the microbiota of inflammasome-deficient mice drive transmissible inflammation-induced CRC. This microbiota-mediated effect is dependent upon micro...

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Bibliographic Details
Main Authors: Bo Hu, Gil Friedman, Eran Elinav, Richard A Flavell
Format: Article
Language:English
Published: Taylor & Francis Group 2019-10-01
Series:OncoImmunology
Subjects:
asc
Online Access:http://dx.doi.org/10.4161/2162402X.2014.981995