Metabolic Profiling of Cognitive Aging in Midlife

Metabolic Profiling of Cognitive Aging in Midlife

Alzheimer’s dementia (AD) begins many years before its clinical symptoms. Metabolic dysfunction represents a core feature of AD and cognitive impairment, but few metabolomic studies have focused on cognitive aging in midlife. Using an untargeted metabolomics approach, we identified metabolic predict...

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Bibliographic Details
Main Authors: Zhiguang Huo, Brinda K. Rana, Jeremy A. Elman, Ruocheng Dong, Corinne D. Engelman, Sterling C. Johnson, Michael J. Lyons, Carol E. Franz, William S. Kremen, Jinying Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
untargeted metabolomics
cognitive change
middle age
twin studies
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.555850/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2020.555850/full

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