N2‐Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle

N2‐Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle

Abstract The role of neutrophils in bone regeneration remains elusive. In this study, it is shown that intramuscular implantation of interleukin‐8 (IL‐8) (commonly recognized as a chemotactic cytokine for neutrophils) at different levels lead to outcomes resembling those of fracture hematoma at vari...

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Bibliographic Details
Main Authors: Bolei Cai, Dan Lin, Yan Li, Le Wang, Jirong Xie, Taiqiang Dai, Fuwei Liu, Mingyue Tang, Lei Tian, Yuan Yuan, Liang Kong, Steve G. F. Shen
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Advanced Science
Subjects:
bone regeneration
interleukin‐8
neutrophils
stem cell recruitment
stromal cell‐derived factor‐1α
Online Access:https://doi.org/10.1002/advs.202100584

Internet

https://doi.org/10.1002/advs.202100584

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