The Cell Wall Polymer Lipoteichoic Acid Becomes Nonessential in Staphylococcus aureus Cells Lacking the ClpX Chaperone

Lipoteichoic acid (LTA) is an important cell wall component of Gram-positive bacteria and a promising target for the development of vaccines and antimicrobial compounds against Staphylococcus aureus. Here we demonstrate that mutations in the conditionally essential ltaS (LTA synthase) gene arise spo...

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Bibliographic Details
Main Authors: Kristoffer T. Bæk, Lisa Bowman, Charlotte Millership, Mia Dupont Søgaard, Volkhard Kaever, Pia Siljamaki, Kirsi Savijoki, Pekka Varmanen, Tuula A. Nyman, Angelika Grundling, Dorte Frees
Format: Article
Language:English
Published: American Society for Microbiology 2016-08-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/4/e01228-16