Therapeutic effects of LASSBio-596 in an elastase-induced mouse model of emphysema

Therapeutic effects of LASSBio-596 in an elastase-induced mouse model of emphysema

Emphysema is an intractable pulmonary disease characterized by an inflammatory process of the airways and lung parenchyma and ongoing remodeling process in an attempt to restore lung structure. There is no effective drug therapy that regenerates lung tissue or prevents the progression of emphysema;...

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Bibliographic Details
Main Authors: Gisele A Padilha, Isabela eHenriques, Miqueias eLopes-Pacheco, Soraia C Abreu, Milena V Oliveira, Marcelo M Morales, Lidia M Lima, Eliezer Jesus Barreiro, Pedro L Silva, Debora G Xisto, Patricia Rieken Macedo Rocco
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Physiology
Subjects:
Emphysema
Inflammation
macrophage
remodeling
Elastic fiber
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00267/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00267/full

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