Dendritic Cell-Based Adjuvant Vaccination Targeting Wilms’ Tumor 1 in Patients with Advanced Colorectal Cancer

Dendritic Cell-Based Adjuvant Vaccination Targeting Wilms’ Tumor 1 in Patients with Advanced Colorectal Cancer

Despite significant recent advances in the development of immune checkpoint inhibitors, the treatment of advanced colorectal cancer involving metastasis to distant organs remains challenging. We conducted a phase I study to investigate the safety and immunogenicity of Wilms’ tumor (WT1) class I/II p...

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Bibliographic Details
Main Authors: Shigetaka Shimodaira, Kenji Sano, Koichi Hirabayashi, Terutsugu Koya, Yumiko Higuchi, Yumiko Mizuno, Naoko Yamaoka, Miki Yuzawa, Takashi Kobayashi, Kenichi Ito, Tomonobu Koizumi
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Vaccines
Subjects:
dendritic cell vaccines
colorectal cancer
Wilms’ tumor 1
immunohistochemistry
tetramer analysis
enzyme-linked immunosorbent spot assay
Online Access:http://www.mdpi.com/2076-393X/3/4/1004

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http://www.mdpi.com/2076-393X/3/4/1004

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