Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers

Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers

BackgroundBlood-based biomarkers have been proposed as an alternative to current sputum-based treatment monitoring methods in active tuberculosis (ATB). The aim of this study was to validate previously described phenotypic, activation, and cytokine markers of treatment response in a West African coh...

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Bibliographic Details
Main Authors: Molly A. Vickers, Fatoumatta Darboe, Caleb N. Muefong, Georgetta Mbayo, Amadou Barry, Awa Gindeh, Sainabou Njie, Abi-Janet Riley, Binta Sarr, Basil Sambou, Hazel M. Dockrell, Salome Charalambous, Andrea Rachow, Olumuyiwa Owolabi, Shamanthi Jayasooriya, Jayne S. Sutherland
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
treatment
activation markers
cytokines
immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.572620/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.572620/full

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