Differential Sensitivity of Target Genes to Translational Repression by miR-17~92.

MicroRNAs (miRNAs) are thought to exert their functions by modulating the expression of hundreds of target genes and each to a small degree, but it remains unclear how small changes in hundreds of target genes are translated into the specific function of a miRNA. Here, we conducted an integrated ana...

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Bibliographic Details
Main Authors: Hyun Yong Jin, Hiroyo Oda, Pengda Chen, Chao Yang, Xiaojuan Zhou, Seung Goo Kang, Elizabeth Valentine, Jennifer M Kefauver, Lujian Liao, Yaoyang Zhang, Alicia Gonzalez-Martin, Jovan Shepherd, Gareth J Morgan, Tony S Mondala, Steven R Head, Pyeung-Hyeun Kim, Nengming Xiao, Guo Fu, Wen-Hsien Liu, Jiahuai Han, James R Williamson, Changchun Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5348049?pdf=render