In Silico Prediction for Intestinal Absorption and Brain Penetration of Chemical Pesticides in Humans

In Silico Prediction for Intestinal Absorption and Brain Penetration of Chemical Pesticides in Humans

Intestinal absorption and brain permeation constitute key parameters of toxicokinetics for pesticides, conditioning their toxicity, including neurotoxicity. However, they remain poorly characterized in humans. The present study was therefore designed to evaluate human intestine and brain permeation...

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Bibliographic Details
Main Authors: Lisa Chedik, Dominique Mias-Lucquin, Arnaud Bruyere, Olivier Fardel
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:International Journal of Environmental Research and Public Health
Subjects:
pesticides
toxicokinetics
intestinal absorption
brain permeation
toxicity
in silico method
prediction
Online Access:http://www.mdpi.com/1660-4601/14/7/708

Internet

http://www.mdpi.com/1660-4601/14/7/708

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